@font-face { font-family: 'Poppins'; src: url('fonts/Poppins-400-latin-ext.woff2') format('woff2'); font-style: normal; font-weight: 400; font-display: swap; unicode-range: U+0100-02BA, U+02BD-02C5, U+02C7-02CC, U+02CE-02D7, U+02DD-02FF, U+0304, U+0308, U+0329, U+1D00-1DBF, U+1E00-1E9F, U+1EF2-1EFF, U+2020, U+20A0-20AB, U+20AD-20C0, U+2113, U+2C60-2C7F, U+A720-A7FF; }
@font-face { font-family: 'Poppins'; src: url('fonts/Poppins-400-latin.woff2') format('woff2'); font-style: normal; font-weight: 400; font-display: swap; unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD; }
@font-face { font-family: 'Poppins'; src: url('fonts/Poppins-500-latin-ext.woff2') format('woff2'); font-style: normal; font-weight: 500; font-display: swap; unicode-range: U+0100-02BA, U+02BD-02C5, U+02C7-02CC, U+02CE-02D7, U+02DD-02FF, U+0304, U+0308, U+0329, U+1D00-1DBF, U+1E00-1E9F, U+1EF2-1EFF, U+2020, U+20A0-20AB, U+20AD-20C0, U+2113, U+2C60-2C7F, U+A720-A7FF; }
@font-face { font-family: 'Poppins'; src: url('fonts/Poppins-500-latin.woff2') format('woff2'); font-style: normal; font-weight: 500; font-display: swap; unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD; }
@font-face { font-family: 'Poppins'; src: url('fonts/Poppins-600-latin-ext.woff2') format('woff2'); font-style: normal; font-weight: 600; font-display: swap; unicode-range: U+0100-02BA, U+02BD-02C5, U+02C7-02CC, U+02CE-02D7, U+02DD-02FF, U+0304, U+0308, U+0329, U+1D00-1DBF, U+1E00-1E9F, U+1EF2-1EFF, U+2020, U+20A0-20AB, U+20AD-20C0, U+2113, U+2C60-2C7F, U+A720-A7FF; }
@font-face { font-family: 'Poppins'; src: url('fonts/Poppins-600-latin.woff2') format('woff2'); font-style: normal; font-weight: 600; font-display: swap; unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD; }
@font-face { font-family: 'Poppins'; src: url('fonts/Poppins-700-latin-ext.woff2') format('woff2'); font-style: normal; font-weight: 700; font-display: swap; unicode-range: U+0100-02BA, U+02BD-02C5, U+02C7-02CC, U+02CE-02D7, U+02DD-02FF, U+0304, U+0308, U+0329, U+1D00-1DBF, U+1E00-1E9F, U+1EF2-1EFF, U+2020, U+20A0-20AB, U+20AD-20C0, U+2113, U+2C60-2C7F, U+A720-A7FF; }
@font-face { font-family: 'Poppins'; src: url('fonts/Poppins-700-latin.woff2') format('woff2'); font-style: normal; font-weight: 700; font-display: swap; unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD; }
@font-face { font-family: 'Poppins'; src: url('fonts/Poppins-800-latin-ext.woff2') format('woff2'); font-style: normal; font-weight: 800; font-display: swap; unicode-range: U+0100-02BA, U+02BD-02C5, U+02C7-02CC, U+02CE-02D7, U+02DD-02FF, U+0304, U+0308, U+0329, U+1D00-1DBF, U+1E00-1E9F, U+1EF2-1EFF, U+2020, U+20A0-20AB, U+20AD-20C0, U+2113, U+2C60-2C7F, U+A720-A7FF; }
@font-face { font-family: 'Poppins'; src: url('fonts/Poppins-800-latin.woff2') format('woff2'); font-style: normal; font-weight: 800; font-display: swap; unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD; }
:root {
  --canvas: #ffffff;
  --ink: #251d2a;
  --charcoal: #251d2a;
  --muted: #665f6b;
  --subtle: #716875;
  --line: #e7dce5;
  --border: #cfbccb;
  --pale: #f7f5f7;
  --section-tint: #faf5f8;
  --section-line: #ebdfe7;
  --accent: #ca3150;
  --primary: #aa357f;
  --magenta: #bd4492;
  --blush: #fcf0f5;
  --radius: 16px;
  --shadow: 0 5px 24px rgba(62, 30, 51, .045);
}
* { box-sizing: border-box; }
html { scroll-behavior: smooth; scroll-padding-top: 104px; }
body { margin: 0; background: var(--canvas); color: var(--ink); font-family: 'Poppins', system-ui, sans-serif; font-size: 16px; line-height: 1.6; -webkit-font-smoothing: antialiased; }
button, input, select { font: inherit; color: inherit; }
button, a, input, select, summary { -webkit-tap-highlight-color: transparent; }
button, summary { cursor: pointer; }
button:disabled, select:disabled { cursor: default; opacity: .65; }
a { color: inherit; text-decoration: none; }
img, svg { max-width: 100%; }
img { display: block; }
p, h1, h2, h3, h4 { margin-top: 0; }
p { margin-bottom: 20px; }
h1, h2, h3, h4 { color: var(--ink); font-weight: 700; }
h1, h2 { line-height: 1.08; letter-spacing: -.03em; }
h2 { font-size: clamp(34px, 4vw, 48px); margin-bottom: 24px; }
h3 { font-size: 24px; line-height: 1.25; letter-spacing: -.025em; margin-bottom: 16px; }
h4 { font-size: 22px; line-height: 1.3; letter-spacing: -.02em; margin-bottom: 16px; }
a, button, summary { touch-action: manipulation; }
a:focus-visible, button:focus-visible, input:focus-visible, select:focus-visible, summary:focus-visible { outline: 2px solid var(--ink); outline-offset: 4px; }
::selection { background: #f4d8e8; color: #000000; }
[hidden] { display: none !important; }
.container { width: min(1200px, calc(100% - 64px)); margin-inline: auto; }
.muted { color: var(--muted); }
.small { font-size: 14px; }
.sr-only { position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0; }
.skip { position: fixed; left: 16px; top: -120px; z-index: 100; padding: 12px 20px; border: 1px solid var(--ink); border-radius: var(--radius); background: var(--canvas); }
.skip:focus { top: 12px; }

/* Navigation */
.header { position: sticky; top: 0; z-index: 30; background: rgba(255,255,255,.97); border-top: 4px solid var(--primary); border-bottom: 1px solid var(--line); }
.header-inner { min-height: 88px; display: flex; align-items: center; justify-content: space-between; gap: 28px; }
.brand { display: inline-flex; align-items: baseline; flex: none; font-size: 34px; font-weight: 800; letter-spacing: -.07em; line-height: 1; }
.brand img { display: block; width: 136px; height: auto; }
.brand span { font-weight: 500; }
.brand .brand-u { font-weight: 400; }
.brand .brand-hyphen { color: var(--subtle); font-weight: 400; }
.brand .brand-sex { color: #000000; font-weight: 800; letter-spacing: -.065em; }
.brand i { width: 6px; height: 6px; margin-left: 4px; border-radius: 50%; background: var(--ink); }
.nav { display: flex; flex-wrap: wrap; align-items: center; justify-content: flex-end; gap: 4px 22px; font-size: 13px; font-weight: 500; }
.nav a { padding: 12px 0; text-underline-offset: 6px; text-decoration-thickness: 1px; }
.nav a:hover, .nav a.current { color: var(--primary); text-decoration: underline; }
.nav a:last-child { padding: 12px 18px; border: 1px solid var(--primary); border-radius: 999px; color: #fff; background: var(--primary); }
.nav a:last-child:hover, .nav a:last-child.current { color: #fff; background: #892565; border-color: #892565; }
.nav a span { margin-left: 8px; }
.menu-button { display: none; align-items: center; gap: 12px; min-height: 44px; padding: 8px 16px; border: 1px solid var(--border); border-radius: 999px; background: var(--canvas); font-size: 14px; }

/* Shared controls and section rhythm */
.button { display: inline-flex; align-items: center; justify-content: center; gap: 22px; min-height: 52px; padding: 14px 28px; border: 1px solid var(--primary); border-radius: 999px; font-size: 15px; font-weight: 600; line-height: 1.4; transition: background-color .15s ease, transform .15s ease; }
.button span { font-size: 20px; line-height: 1; }
.primary { background: var(--accent); color: #fff; border-color: var(--accent); box-shadow: 0 6px 20px rgba(110, 20, 48, .12); }
.primary:hover { background: #a92440; border-color: #a92440; }
.text-link, .light-link { display: inline-flex; align-items: center; gap: 12px; width: fit-content; color: var(--primary); font-size: 14px; font-weight: 600; line-height: 1.5; text-underline-offset: 5px; }
.text-link:hover, .light-link:hover { text-decoration: underline; }
.text-link span, .light-link span { flex: none; }
.eyebrow { display: flex; align-items: center; gap: 10px; margin-bottom: 24px; color: var(--primary); font-size: 11px; font-weight: 600; line-height: 1.6; letter-spacing: .14em; }
.dot { display: inline-block; flex: none; width: 6px; height: 6px; border-radius: 50%; background: currentColor; }
.pill { display: inline-flex; align-items: center; gap: 7px; padding: 5px 10px; border: 1px solid var(--border); border-radius: var(--radius); font-size: 11px; font-weight: 600; line-height: 1.5; white-space: nowrap; }
.pill .dot { width: 5px; height: 5px; }
.section { padding-block: 96px; }
.section-top { display: flex; align-items: center; justify-content: space-between; gap: 24px; margin-bottom: 32px; }
.section-top .eyebrow { margin: 0; }
.section-meta { color: var(--subtle); font-size: 12px; text-align: right; }
.intro-grid { display: grid; grid-template-columns: minmax(0, 1.1fr) minmax(0, 1fr); align-items: start; gap: 80px; margin-bottom: 40px; }
.intro-grid > p, .intro-grid > div > p { max-width: 560px; color: var(--muted); font-size: 16px; }
.intro-grid > div > .small { font-size: 14px; }
.intro-grid h2, .intro-grid > p:last-child, .intro-grid > div > p:last-child { margin-bottom: 0; }
.editorial-note { margin: 24px 0 0; color: var(--subtle); font-size: 12px; line-height: 1.7; }

/* Introduction */
.hero { position: relative; overflow: hidden; padding-block: 88px 110px; background: linear-gradient(115deg,#251a2c 0%,#4d2645 55%,#88376b 100%); }
.hero-centered { display: block; text-align: center; }
.hero-copy { position: relative; z-index: 1; max-width: 760px; margin: 0; }
.hero .eyebrow { justify-content: flex-start; color: #f4b5d4; margin-bottom: 28px; }
h1 { margin: 0 0 28px; font-size: clamp(52px, 7vw, 92px); font-weight: 800; }
h1 em { font: inherit; color: inherit; }
.hero-lede { max-width: 620px; margin: 0 0 32px; color: #f0e4ef; font-size: 17px; line-height: 1.8; }
.hero-actions { display: flex; flex-wrap: wrap; align-items: center; justify-content: flex-start; gap: 22px 28px; }
.hero-actions .text-link { font-size: 16px; }
.hero-facts { position: relative; z-index: 2; display: grid; grid-template-columns: repeat(3,minmax(0,1fr)); gap: 24px; margin-top: -42px; margin-bottom: 64px; padding: 0; }
.hero-facts > div { min-width: 0; padding: 32px; border: 1px solid var(--line); border-radius: var(--radius); background: #fff; box-shadow: var(--shadow); }
.hero-facts > div + div { border-left: 1px solid var(--line); }
.hero-facts strong { display: block; margin-bottom: 8px; color: var(--primary); font-size: 28px; font-weight: 700; letter-spacing: -.025em; line-height: 1.3; }
.hero-facts span { color: var(--subtle); font-size: 14px; }
.mission-strip { border-block: 1px solid var(--line); background: var(--pale); }
.mission-strip .container { display: flex; justify-content: space-between; align-items: center; gap: 24px; padding-block: 24px; color: var(--muted); font-size: 13px; }
.mission-strip span::before { content: '↗'; margin-right: 12px; color: var(--accent); }

/* Origins, founders and study editions */
.history-grid { display: grid; grid-template-columns: minmax(0, 1fr) minmax(0, 1.06fr); align-items: start; gap: 64px; }
.history-grid h2 { font-size: clamp(34px, 3.6vw, 46px); }
.history-photo { margin: 32px 0 0; }
.history-photo img { width: 100%; height: auto; border: 1px solid var(--line); border-radius: var(--radius); filter: grayscale(1); }
.history-photo figcaption { margin-top: 12px; color: var(--subtle); font-size: 12px; line-height: 1.6; }
.history-copy p { margin-bottom: 22px; color: var(--muted); font-size: 16px; line-height: 1.7; }
.history-copy .history-mission { margin: 28px 0 0; padding: 24px; border-left: 3px solid var(--primary); border-radius: 0 12px 12px 0; background: var(--blush); color: var(--ink); font-weight: 500; }
.founders { margin-top: 56px; padding: 36px 28px; border: 1px solid var(--line); border-radius: var(--radius); background: var(--pale); }
.founders > .eyebrow { margin-bottom: 24px; }
.founder-list { display: grid; grid-template-columns: repeat(3, minmax(0, 1fr)); gap: 32px; }
.founder { display: flex; flex-direction: column; align-items: center; gap: 20px; min-width: 0; text-align: center; }
.founder > div:last-child { min-width: 0; width: 100%; max-width: 330px; }
.founder-portrait { flex: none; width: min(190px, 100%); height: 210px; overflow: hidden; border: 1px solid var(--line); border-radius: var(--radius); background: var(--pale); }
.founder img { width: 100%; height: 100%; object-fit: contain; object-position: center; }
.founder h3 { margin: 0 0 8px; font-size: 20px; line-height: 1.35; letter-spacing: -.02em; overflow-wrap: anywhere; }
.founder p { margin: 0; color: var(--muted); font-size: 14px; line-height: 1.5; }
.founder .founder-profession { color: var(--ink); font-size: 15px; line-height: 1.55; }
.founder .founder-affiliation { margin-top: 8px; font-size: 14px; }
.photo-credits { margin: 20px 0 0; color: var(--subtle); font-size: 11px; line-height: 1.7; }
.photo-credits summary { width: fit-content; }
.photo-credits p { margin: 8px 0 0; }
.photo-credits a { text-decoration: underline; text-underline-offset: 3px; }
.timeline { display: grid; grid-template-columns: repeat(3, minmax(0, 1fr)); gap: 24px; margin-top: 40px; }
.timeline article { display: flex; flex-direction: column; min-width: 0; padding: 30px; border: 1px solid var(--line); border-radius: var(--radius); background: var(--canvas); box-shadow: var(--shadow); }
.phase-head { display: flex; flex-wrap: wrap; align-items: center; justify-content: space-between; gap: 12px; margin-bottom: 28px; color: var(--muted); font-size: 11px; }
.phase-number { display: grid; place-items: center; flex: none; width: 40px; height: 40px; border: 0; border-radius: 12px; background: var(--blush); color: var(--primary); font-size: 15px; font-weight: 600; }
.timeline h3 { margin-bottom: 16px; font-size: 30px; }
.timeline p { margin-bottom: 24px; color: var(--muted); font-size: 15px; line-height: 1.6; }
.timeline .text-link { margin-top: auto; }
.timeline .current-phase { background: var(--blush); border-color: #d8a6c5; }
.learnings { margin-top: 64px; padding-top: 40px; border-top: 1px solid var(--line); }
.learnings-heading { display: flex; align-items: flex-start; justify-content: space-between; gap: 64px; margin-bottom: 32px; }
.learnings-heading .eyebrow { margin-bottom: 16px; }
.learnings-heading h3 { margin: 0; font-size: 34px; letter-spacing: -.04em; }
.learnings-heading > p { max-width: 470px; margin: 0; color: var(--muted); font-size: 16px; }
.findings-grid { display: grid; grid-template-columns: repeat(2,minmax(0,1fr)); gap: 24px; }
.findings-grid article { padding: 30px; border: 1px solid var(--line); border-radius: var(--radius); background: var(--canvas); box-shadow: var(--shadow); }
.finding-study { margin-bottom: 14px; color: var(--primary); font-size: 12px; font-weight: 600; letter-spacing: .06em; }
.findings-grid article > p:not(.finding-study) { margin-bottom: 16px; color: var(--muted); font-size: 16px; }
.all-results { margin-top: 32px; }

/* Current study and aggregate data */
.data-section { position: relative; padding-block: 96px; border-block: 1px solid var(--section-line); background: var(--section-tint); }
.data-heading { display: flex; align-items: flex-start; justify-content: space-between; gap: 24px; }
.data-heading > div { min-width: 0; }
.data-heading h2 { margin-bottom: 20px; }
.data-heading p { max-width: 750px; color: var(--muted); font-size: 16px; }
.inverse { background: var(--canvas); }
.refresh-button { display: inline-flex; align-items: center; gap: 12px; flex: none; min-height: 44px; padding: 10px 18px; border: 1px solid var(--border); border-radius: 999px; background: var(--canvas); color: var(--primary); font-size: 14px; }
.refresh-button:hover:not(:disabled) { background: #ededee; }
.refresh-button span { font-size: 20px; line-height: 1; }
.data-status { display: flex; align-items: flex-start; gap: 10px; margin-top: 8px; color: var(--muted); font-size: 13px; line-height: 1.7; }
.status-mark { flex: none; width: 6px; height: 6px; margin-top: 8px; border: 1px solid var(--muted); border-radius: 50%; }
.data-status.live .status-mark { background: #248166; border-color: #248166; }
.metrics { display: grid; grid-template-columns: repeat(4, minmax(0, 1fr)); gap: 20px; margin-block: 28px; }
.metric { display: flex; flex-direction: column; min-width: 0; padding: 28px; border: 1px solid var(--line); border-radius: var(--radius); background: var(--canvas); box-shadow: var(--shadow); }
.metric:nth-child(even) { background: var(--canvas); }
.metric > span { min-height: 42px; color: var(--muted); font-size: 14px; line-height: 1.5; }
.metric strong { display: block; margin-top: 12px; color: var(--primary); font-size: clamp(36px,3.8vw,48px); font-weight: 700; letter-spacing: -.04em; line-height: 1.15; overflow-wrap: anywhere; font-variant-numeric: tabular-nums; }
.metric strong small { font-size: .5em; letter-spacing: -.02em; }
.metric p { margin: 12px 0 0; color: var(--subtle); font-size: 12px; line-height: 1.6; }
.variables-panel { display: grid; grid-template-columns: minmax(0,1fr) minmax(0,1.15fr); gap: 40px; align-items: center; padding: 32px; border: 1px solid var(--line); border-radius: var(--radius); background: var(--canvas); }
.variable-controls { min-width: 0; }
.variable-controls label { display: block; margin-bottom: 12px; font-size: 16px; font-weight: 600; }
.variable-controls select { width: 100%; min-width: 0; max-width: 100%; padding: 12px; border: 1px solid var(--border); border-radius: var(--radius); background: var(--canvas); font-size: 16px; text-overflow: ellipsis; }
.variable-controls p { max-width: 400px; margin: 12px 0 0; color: var(--subtle); font-size: 13px; }
.variable-result { min-width: 0; padding-left: 40px; border-left: 1px solid var(--line); }
.variable-result > span { display: block; color: var(--muted); font-size: 14px; }
.variable-result strong { display: block; margin-block: 8px; font-size: 44px; font-weight: 600; line-height: 1.2; letter-spacing: -.045em; overflow-wrap: anywhere; }
.variable-result strong small { font-size: 22px; letter-spacing: -.02em; }
.variable-result p { margin: 6px 0 0; color: var(--muted); font-size: 14px; line-height: 1.6; overflow-wrap: anywhere; }
.data-bottom { display: flex; justify-content: space-between; align-items: flex-start; gap: 32px; margin-top: 28px; }
.data-bottom p { max-width: 800px; margin: 0; color: var(--subtle); font-size: 12px; line-height: 1.7; }
.data-bottom .light-link { flex: none; }
.anchor-alias { position: absolute; top: 0; }

/* Search, selectors and filters */
.publication-tools, .directory-tools, .team-tools { display: flex; align-items: center; flex-wrap: wrap; gap: 20px; margin-bottom: 24px; padding: 18px; border: 1px solid var(--line); border-radius: var(--radius); background: var(--pale); }
.publication-tools { justify-content: space-between; }
.search { display: flex; align-items: center; width: 100%; max-width: 350px; min-width: 0; border: 1px solid var(--border); border-radius: var(--radius); background: var(--canvas); }
.search input { width: 100%; min-width: 0; min-height: 46px; padding: 11px 14px; border: 0; border-radius: var(--radius); background: transparent; color: var(--ink); font-size: 16px; line-height: 1.5; }
.search input::placeholder { color: var(--subtle); opacity: 1; }
.search input:focus-visible { outline-offset: -3px; }
.search > span:not(.sr-only) { flex: none; margin-right: 14px; color: var(--subtle); font-size: 24px; line-height: 1; }
.scope-label { display: flex; align-items: center; gap: 12px; min-width: 0; color: var(--muted); font-size: 14px; }
.scope-label select { min-width: 0; max-width: 100%; min-height: 48px; padding: 10px 12px; border: 1px solid var(--border); border-radius: var(--radius); background: var(--canvas); color: var(--ink); font-size: 16px; }
.result-count { margin-left: auto; color: var(--subtle); font-size: 12px; }
.directory-tools > .result-count { max-width: 270px; text-align: right; }
.filter-tabs { display: flex; gap: 4px; max-width: 100%; border: 0; }
.filter-tabs button { min-height: 44px; padding: 10px 16px; border: 0; border-radius: 999px; background: transparent; color: var(--muted); font-size: 14px; line-height: 1.5; white-space: nowrap; }
.filter-tabs button.active { color: #fff; background: var(--primary); font-weight: 600; }
.filter-tabs button:not(.active):hover { background: var(--pale); color: var(--ink); }
.empty { margin: 24px 0; padding: 24px; border: 1px dashed var(--border); border-radius: var(--radius); color: var(--muted); font-size: 16px; text-align: center; }

/* Clinical and community centers */
.network-section { padding-block: 64px; border-block: 1px solid var(--section-line); background: #f2ebf0; }
.network-section > .centers-section, .network-section > .investigators-section { width: min(1280px, calc(100% - 64px)); margin-inline: auto; background: var(--canvas); }
.network-section > .centers-section { border-radius: var(--radius) var(--radius) 0 0; }
.network-section > .centers-section > .container { width: calc(100% - 80px); max-width: 1200px; }
.network-section > .investigators-section { padding-inline: 40px; border-radius: 0 0 var(--radius) var(--radius); }
.centers-section { background: var(--canvas); }
.center-list { display: grid; grid-template-columns: repeat(3, minmax(0, 1fr)); gap: 0 32px; margin: 0; padding: 0; list-style: none; }
.center-list li { display: flex; align-items: flex-start; gap: 14px; min-width: 0; padding-block: 22px; border-bottom: 1px solid var(--line); }
.center-list li > div { min-width: 0; }
.center-icon { display: grid; place-items: center; flex: none; width: 30px; height: 30px; border: 0; border-radius: 9px; background: var(--blush); color: var(--primary); font-size: 21px; line-height: 1; }
.center-list h3 { margin: 0 0 6px; font-size: 16px; font-weight: 600; line-height: 1.45; letter-spacing: -.01em; overflow-wrap: anywhere; }
.center-list li div > span { display: block; color: var(--subtle); font-size: 13px; line-height: 1.6; overflow-wrap: anywhere; }
.affiliated-centers { margin-top: 32px; padding: 20px; border: 1px solid var(--border); border-radius: var(--radius); background: var(--pale); }
.affiliated-centers > summary { padding-block: 6px; font-size: 16px; font-weight: 600; }
.affiliated-centers > summary > span { display: inline-block; margin-left: 8px; padding: 2px 8px; border: 1px solid var(--border); border-radius: var(--radius); font-size: 12px; font-weight: 400; }
.affiliated-centers > p { margin: 18px 0 0; color: var(--muted); font-size: 14px; }

/* Investigators and documented participation */
.investigators-section { border-top: 1px solid var(--line); }
.team-directory { margin-top: 24px; border-block: 1px solid var(--line); }
.team-directory > summary { display: flex; align-items: center; justify-content: space-between; gap: 24px; padding-block: 24px; font-size: 20px; font-weight: 500; line-height: 1.4; list-style: none; }
.team-directory > summary::-webkit-details-marker { display: none; }
.team-directory > summary::marker { content: ''; }
.summary-action { display: inline-flex; align-items: center; flex: none; gap: 16px; color: var(--muted); font-size: 14px; font-weight: 400; }
.summary-action > span { display: inline-block; font-size: 24px; line-height: 1; }
.team-directory[open] .summary-action > span { transform: rotate(45deg); }
.member-count { display: inline-block; margin-left: 8px; padding: 2px 8px; border: 1px solid var(--border); border-radius: var(--radius); font-size: 12px; }
.team-tools { padding-top: 18px; }
.team-tools .search { max-width: 370px; }
.team-search { margin-bottom: 24px; }
.member-list { display: grid; grid-template-columns: repeat(2, minmax(0, 1fr)); align-items: start; gap: 0 40px; margin: 0; padding: 0 0 16px; list-style: none; }
.member-card { min-width: 0; padding-block: 28px; border-top: 1px solid var(--line); scroll-margin-top: 108px; }
.member-list strong { display: block; margin-bottom: 10px; font-size: 18px; font-weight: 600; line-height: 1.4; letter-spacing: -.015em; overflow-wrap: anywhere; }
.member-affiliation { margin: 0 0 10px; color: var(--muted); font-size: 14px; line-height: 1.65; white-space: pre-line; overflow-wrap: anywhere; }
.member-affiliation > span { font-size: 12px; }
.member-list li > .member-studies { display: block; color: var(--subtle); font-size: 12px; }
.member-list li > .signature-note { display: block; margin-bottom: 10px; color: var(--muted); font-size: 12px; line-height: 1.6; font-style: italic; overflow-wrap: anywhere; }
.member-works { margin-top: 16px; }
.member-works > summary { width: fit-content; padding-block: 6px; color: var(--primary); font-size: 14px; font-weight: 500; }
.member-work { padding-block: 20px; border-top: 1px solid var(--line); }
.member-work:first-child { margin-top: 12px; }
.member-work-meta { display: block; margin-bottom: 8px; color: var(--subtle); font-size: 11px; line-height: 1.7; }
.member-work .member-source { display: block; font-size: 15px; font-weight: 600; line-height: 1.5; overflow-wrap: anywhere; text-underline-offset: 4px; }
.member-source:hover { text-decoration: underline; }
.member-work-venue { display: block; margin-top: 8px; color: var(--muted); font-size: 12px; line-height: 1.6; overflow-wrap: anywhere; }
.member-work p { margin: 10px 0 0; color: var(--muted); font-size: 13px; line-height: 1.65; white-space: pre-line; overflow-wrap: anywhere; }
.member-work .member-work-note { color: var(--subtle); font-size: 12px; font-style: italic; }
.card-delivery { display: flex; align-items: center; gap: 28px; margin-top: 40px; padding: 32px; border: 1px solid var(--border); border-radius: var(--radius); background: var(--pale); }
.delivery-icon { flex: none; font-size: 40px; line-height: 1; }
.card-delivery > div:nth-child(2) { min-width: 0; }
.card-delivery .eyebrow { margin-bottom: 12px; font-size: 11px; }
.card-delivery h3 { margin-bottom: 12px; }
.card-delivery p:not(.eyebrow) { max-width: 560px; margin: 0; color: var(--muted); font-size: 14px; }
.card-delivery .button, .pending-label { flex: none; margin-left: auto; }
.pending-label { padding: 8px 12px; border: 1px solid var(--border); border-radius: var(--radius); color: var(--muted); font-size: 12px; }

/* Publication library */
.publications-intro { margin-bottom: 32px; }
.catalog-count { margin: 4px 0 16px; color: var(--subtle); font-size: 13px; }
.publication-list { display: grid; gap: 20px; border: 0; }
.publication { display: grid; grid-template-columns: 82px minmax(0,1fr) 44px; gap: 28px; padding: 30px; border: 1px solid var(--line); border-radius: var(--radius); background: #fff; box-shadow: var(--shadow); scroll-margin-top: 108px; }
.publication-body { min-width: 0; }
.publication-year { color: var(--primary); font-size: 28px; font-weight: 600; letter-spacing: -.03em; line-height: 1.3; }
.publication-year > span { display: block; margin-top: 6px; color: var(--subtle); font-size: 11px; font-weight: 500; letter-spacing: .03em; line-height: 1.6; text-transform: uppercase; }
.publication-journal { margin-bottom: 12px; color: var(--subtle); font-size: 13px; line-height: 1.6; overflow-wrap: anywhere; }
.publication-tags { display: flex; flex-wrap: wrap; align-items: center; gap: 8px; margin-bottom: 16px; color: var(--muted); font-size: 11px; }
.publication-tags > span { padding: 3px 9px; border: 1px solid var(--border); border-radius: var(--radius); }
.publication-tags .submitted, .publication-tags .scheduled { border-style: dashed; }
.publication-tags .accepted { background: var(--pale); border-color: var(--border); }
.publication h3 { margin-bottom: 14px; font-size: 22px; font-weight: 600; line-height: 1.4; letter-spacing: -.025em; overflow-wrap: anywhere; }
.publication h3 a { text-underline-offset: 4px; text-decoration-thickness: 1px; }
.publication h3 a:hover { text-decoration: underline; }
.publication-summary { margin-bottom: 12px; color: var(--muted); font-size: 15px; line-height: 1.65; overflow-wrap: anywhere; }
.publication-arrow { display: grid; place-items: center; align-self: start; width: 44px; height: 44px; border: 1px solid var(--line); border-radius: 50%; background: var(--blush); color: var(--primary); font-size: 24px; line-height: 1; }
.publication-arrow:hover { background: var(--pale); border-color: var(--charcoal); }
.author-details { color: var(--muted); font-size: 14px; }
.author-details summary { display: list-item; width: fit-content; padding-block: 6px; color: var(--primary); font-size: 14px; }
.author-details p { margin: 12px 0 0; line-height: 1.8; overflow-wrap: anywhere; }

/* Institutional logos retain their original artwork and colors. */
.partner-strip { display: flex; align-items: center; justify-content: center; gap: 32px; padding-block: 0 80px; }
.partner-strip > p { margin: 0; color: var(--subtle); font-size: 12px; }
.partner-strip > div { display: flex; align-items: center; gap: 40px; }
.partner-strip a { display: flex; flex-direction: column; align-items: center; }
.partner-strip a span { color: var(--muted); font-size: 12px; text-align: center; }
.partner-cross { color: var(--subtle); }
.institution-strip { flex-direction: column; gap: 32px; }
.institution-strip > p { font-size: 11px; font-weight: 600; letter-spacing: .1em; text-transform: uppercase; }
.institution-strip > .institution-logos { display: grid; grid-template-columns: repeat(3, minmax(0, 1fr)); align-items: start; gap: 48px; width: min(850px, 100%); }
.institution-logos > a { min-width: 0; gap: 16px; padding: 12px; border-radius: var(--radius); }
.institution-logos > a:hover > span { text-decoration: underline; text-underline-offset: 4px; }
.institution-logos img { width: 180px; height: 100px; object-fit: contain; }
.institution-logos .logo-geits { width: 100px; }
.institution-logos .logo-fsg { width: 165px; }
.institution-logos > a > span { max-width: 220px; font-size: 12px; line-height: 1.6; }

/* Footer */
.footer { border-top: 0; background: #17121b; color: #fff; }
.footer-top { display: flex; align-items: center; justify-content: space-between; gap: 40px; padding-block: 56px; }
.footer-top p { margin: 0 auto 0 16px; color: #e2d8e2; font-size: 15px; }
.footer-bottom { display: flex; align-items: flex-start; justify-content: space-between; gap: 32px; padding-block: 28px; border-top: 1px solid #49384a; color: #d2c6d2; font-size: 12px; }
.footer-bottom details { max-width: 560px; }
.footer-bottom details summary { text-align: center; }
.footer-bottom details p { margin: 16px 0 0; font-size: 13px; line-height: 1.7; }
.footer-bottom > span { flex: none; }

@media (max-width: 1180px) {
  .header-inner { gap: 24px; }
  .nav { gap: 0 16px; font-size: 13px; }
  .nav a:last-child { padding-inline: 12px; }
  .intro-grid, .history-grid { gap: 40px; }
  .founder-list { gap: 24px; }
  .founder { flex-direction: column; }
  .phase-head { align-items: flex-start; flex-direction: column; }
  .phase-head > span:last-child { display: inline-flex; align-items: center; min-height: 27px; }
  .metrics { gap: 16px; }
  .metric { padding: 20px; }
  .directory-tools > .result-count { flex-basis: 100%; max-width: none; margin-left: 0; text-align: left; }
}
@media (max-width: 960px) {
  html { scroll-padding-top: 92px; }
  .header-inner { position: relative; min-height: 76px; flex-wrap: wrap; gap: 0 24px; }
  .brand { font-size: 32px; }
  .menu-button { display: inline-flex; }
  .nav { width: 100%; padding-block: 12px; font-size: 15px; }
  .js .nav { display: none; position: absolute; top: 100%; left: -32px; right: -32px; width: auto; max-height: calc(100dvh - 76px); overflow-y: auto; padding: 12px 32px 20px; border-bottom: 1px solid var(--border); background: var(--canvas); }
  .js .nav.open { display: flex; flex-direction: column; align-items: stretch; gap: 0; }
  .nav a { padding: 14px 0; }
  .nav a:last-child { margin-top: 8px; padding: 12px 16px; }
  .hero { padding-block: 64px 48px; }
  .hero-facts { margin-top: 48px; }
  .hero-facts strong { font-size: 22px; }
  .mission-strip .container { gap: 16px; font-size: 12px; }
  .mission-strip span::before { margin-right: 8px; }
  .section, .data-section { padding-block: 64px; }
  .intro-grid { gap: 32px; }
  .history-grid { grid-template-columns: 1fr; gap: 32px; }
  .history-photo { max-width: 640px; }
  .history-copy { max-width: 740px; }
  .founder-list { gap: 28px; }
  .timeline { gap: 16px; }
  .timeline article { padding: 20px; }
  .timeline .text-link { font-size: 13px; }
  .learnings-heading { gap: 32px; }
  .learnings-heading > p { max-width: 380px; }
  .findings-grid { gap: 32px; }
  .metrics { grid-template-columns: repeat(2, minmax(0, 1fr)); }
  .metric > span { min-height: 0; }
  .metric strong { font-size: 44px; }
  .variables-panel { gap: 24px; padding: 24px; }
  .variable-result { padding-left: 24px; }
  .data-bottom { flex-direction: column; gap: 20px; }
  .center-list { grid-template-columns: repeat(2, minmax(0, 1fr)); }
  .network-section { padding-block: 32px; }
  .network-section > .centers-section, .network-section > .investigators-section { width: calc(100% - 40px); }
  .network-section > .centers-section > .container { width: calc(100% - 48px); }
  .network-section > .investigators-section { padding-inline: 24px; }
  .member-list { gap: 0 32px; }
  .team-tools .search { max-width: none; flex-basis: 100%; }
  .card-delivery { flex-wrap: wrap; }
  .card-delivery > div:nth-child(2) { flex: 1 1 70%; }
  .card-delivery .button, .pending-label { margin-left: 0; }
  .publication-tools .search { max-width: none; }
  .publication-tools { gap: 20px; }
  .publication { grid-template-columns: 74px minmax(0, 1fr) 44px; gap: 24px; }
  .institution-strip > .institution-logos { gap: 24px; }
  .footer-bottom { gap: 24px; }
}
@media (max-width: 640px) {
  .container { width: calc(100% - 40px); }
  h2, .history-grid h2 { font-size: clamp(32px, 7.5vw, 40px); }
  .header-inner { min-height: 72px; }
  .js .nav { left: -20px; right: -20px; padding-inline: 20px; max-height: calc(100dvh - 72px); }
  .hero { padding-block: 48px 36px; }
  .hero .eyebrow { margin-bottom: 24px; font-size: 11px; letter-spacing: .07em; }
  h1 { font-size: clamp(46px, 10.8vw, 66px); margin-bottom: 24px; }
  .hero-lede { margin-bottom: 28px; font-size: 16px; }
  .hero-actions { gap: 20px; }
  .hero-actions .text-link { font-size: 15px; }
  .hero-facts { gap: 0; margin-top: 40px; padding-top: 24px; }
  .hero-facts > div { padding-inline: 12px; }
  .hero-facts > div:first-child { padding-left: 0; }
  .hero-facts > div:last-child { padding-right: 0; }
  .hero-facts strong { font-size: 18px; }
  .hero-facts span { display: block; font-size: 12px; line-height: 1.5; }
  .mission-strip .container { flex-direction: column; align-items: flex-start; gap: 8px; padding-block: 20px; font-size: 13px; }
  .section, .data-section { padding-block: 48px; }
  .section-top { align-items: flex-start; margin-bottom: 28px; gap: 16px; }
  .section-meta { display: none; }
  .intro-grid { grid-template-columns: 1fr; gap: 24px; margin-bottom: 32px; }
  .intro-grid > p, .intro-grid > div > p { font-size: 15px; }
  .intro-grid > div > .small { font-size: 14px; }
  .history-grid { gap: 28px; }
  .history-photo { margin-top: 24px; }
  .history-copy p { font-size: 15px; }
  .founders { margin-top: 32px; padding-block: 28px; }
  .founder-list { grid-template-columns: 1fr; gap: 36px; }
  .founder { flex-direction: column; gap: 20px; }
  .founder-portrait { width: min(170px, 100%); height: 190px; }
  .founder h3 { font-size: 20px; }
  .founder .founder-affiliation { font-size: 14px; }
  .timeline { grid-template-columns: 1fr; margin-top: 32px; gap: 20px; }
  .timeline article { padding: 24px; }
  .phase-head { flex-direction: row; align-items: center; margin-bottom: 24px; }
  .timeline .text-link { font-size: 14px; }
  .learnings { margin-top: 48px; padding-top: 32px; }
  .learnings-heading { display: block; margin-bottom: 28px; }
  .learnings-heading h3 { margin-bottom: 20px; font-size: 30px; }
  .learnings-heading > p { max-width: none; font-size: 15px; }
  .findings-grid { grid-template-columns: 1fr; gap: 28px; }
  .findings-grid article > p:not(.finding-study) { font-size: 15px; }
  .findings-grid h4 { font-size: 22px; }
  .data-heading { flex-wrap: wrap; gap: 0; }
  .data-heading p { font-size: 15px; }
  .refresh-button { margin-bottom: 20px; }
  .data-status { font-size: 12px; }
  .metrics { gap: 12px; margin-block: 24px; }
  .metric { padding: 18px 16px; }
  .metric > span { min-height: 42px; font-size: 13px; }
  .metric strong { font-size: 38px; }
  .metric p { font-size: 11px; }
  .variables-panel { grid-template-columns: 1fr; padding: 24px 20px; gap: 24px; }
  .variable-controls p { max-width: none; }
  .variable-result { padding: 24px 0 0; border-left: 0; border-top: 1px solid var(--line); }
  .variable-result strong { font-size: 40px; }
  .publication-tools, .directory-tools, .team-tools { padding: 14px 12px; }
  .directory-tools, .team-tools { gap: 16px; }
  .affiliated-centers { padding: 18px 14px; }
  .directory-tools .search, .team-tools .search { max-width: none; flex-basis: 100%; }
  .scope-label { width: 100%; justify-content: space-between; }
  .scope-label select { width: min(70%, 300px); }
  .result-count { margin-left: 0; }
  .center-list { grid-template-columns: 1fr; }
  .network-section { padding-block: 24px; }
  .network-section > .centers-section, .network-section > .investigators-section { width: calc(100% - 24px); }
  .network-section > .centers-section > .container { width: calc(100% - 32px); }
  .network-section > .investigators-section { padding-inline: 16px; }
  .center-list li { padding-block: 20px; }
  .team-directory > summary { gap: 16px; font-size: 18px; }
  .summary-action { gap: 10px; font-size: 12px; }
  .member-list { grid-template-columns: 1fr; }
  .member-card { padding-block: 24px; }
  .card-delivery { margin-top: 32px; padding: 24px; gap: 24px; }
  .delivery-icon { display: none; }
  .card-delivery > div:nth-child(2) { flex-basis: 100%; }
  .publication { grid-template-columns: minmax(0, 1fr) 44px; gap: 16px; padding-block: 28px; }
  .publication-year { grid-column: 1; display: flex; align-items: baseline; flex-wrap: wrap; gap: 12px; font-size: 24px; }
  .publication-year > span { display: inline; margin-top: 0; }
  .publication-body { grid-column: 1 / -1; grid-row: 2; }
  .publication-arrow { grid-column: 2; grid-row: 1; }
  .publication h3 { font-size: 21px; }
  .publication-journal { font-size: 12px; }
  .publication-summary { font-size: 14px; }
  .filter-tabs { width: 100%; }
  .filter-tabs button { flex: 1; padding-inline: 10px; font-size: 14px; }
  .partner-strip { padding-bottom: 48px; }
  .institution-strip > .institution-logos { grid-template-columns: 1fr; gap: 24px; }
  .institution-logos > a { gap: 12px; }
  .institution-logos img { width: 180px; height: 84px; }
  .institution-logos .logo-geits { width: 84px; }
  .institution-logos .logo-fsg { width: 160px; }
  .footer-top { flex-wrap: wrap; gap: 24px; padding-block: 32px; }
  .footer-top p { margin: 0 0 0 auto; font-size: 14px; }
  .footer-top .text-link { flex-basis: 100%; }
  .footer-bottom { flex-wrap: wrap; gap: 20px; font-size: 11px; }
  .footer-bottom details { order: 3; flex-basis: 100%; max-width: none; }
  .footer-bottom details summary { text-align: left; }
}
@media (max-width: 400px) {
  .container { width: calc(100% - 32px); }
  .js .nav { left: -16px; right: -16px; padding-inline: 16px; }
  .hero .eyebrow { max-width: 280px; margin-inline: auto; letter-spacing: .04em; }
  .hero-actions { flex-direction: column; gap: 20px; }
  .hero-facts > div { padding-inline: 8px; }
  .hero-facts strong { font-size: 16px; }
  .hero-facts span { font-size: 11px; }
  .phase-head { gap: 10px; }
  .timeline article { padding: 20px; }
  .metrics { gap: 10px; }
  .metric { padding: 16px 12px; }
  .metric strong { font-size: 34px; }
  .team-directory > summary { align-items: flex-start; flex-direction: column; gap: 12px; }
  .filter-tabs button { padding-inline: 6px; font-size: 13px; }
  .scope-label { flex-direction: column; align-items: stretch; gap: 8px; }
  .scope-label select { width: 100%; }
  .card-delivery { padding: 20px; }
  .footer-top { gap: 20px; }
  .footer-top p { font-size: 13px; }
}
.study-collaboration { display: grid; grid-template-columns: 230px minmax(0,1fr); gap: 40px; align-items: center; margin-top: 40px; padding: 32px; border: 1px solid var(--line); border-radius: var(--radius); background: #fff; box-shadow: var(--shadow); }
.collaboration-identity {text-align:center;}
.collaboration-identity img {display:block;width:100%;height:auto;max-width:230px;margin-inline:auto;}
.collaboration-identity > span {display:block;color:var(--muted);font-size:12px;margin-top:14px;}
.study-collaboration h3 {font-size:25px;line-height:1.25;letter-spacing:-.03em;margin:0 0 14px;}
.study-collaboration p:not(.eyebrow) {font-size:15px;line-height:1.7;color:var(--muted);margin:0;}
.study-collaboration .meeting-note {display:grid;gap:6px;border-top:1px solid var(--line);padding-top:18px;margin-top:18px!important;}
.meeting-note strong {color:var(--ink);font-size:14px;}
@media(max-width:640px){.study-collaboration{grid-template-columns:1fr;gap:28px;padding:24px;}.collaboration-identity img{max-width:205px;}.study-collaboration h3{font-size:23px;}}
@media (prefers-reduced-motion: reduce) {
  html { scroll-behavior: auto; }
  *, *::before, *::after { transition: none !important; }
}

/* Original USEX composition within the FSG-inspired visual system. */
.hero-inner { display:grid; grid-template-columns:minmax(0,1.45fr) minmax(0,1fr); align-items:center; gap:40px; }
.hero-fsg h1 { color:#fff; line-height:1.04; letter-spacing:-.045em; }
.hero-fsg h1 em { color:#f4b5d4; }
.hero-fsg .text-link { color:#fff; }
.hero-art { position:relative; min-width:0; }
.hero-art img { width:100%; height:auto; }
.hero-facts > div > span { display:block; color:var(--muted); font-size:14px; }
.metric:nth-child(even) strong { color:var(--accent); }
.footer .text-link { color:#f4b5d4; }
.footer a:focus-visible, .footer summary:focus-visible { outline-color:#f4b5d4; }
.hero a:focus-visible { outline-color:#fff; }
@media(max-width:960px) {
  .hero-fsg { padding-block:72px 90px; }
  .hero-inner { grid-template-columns:minmax(0,1.5fr) minmax(0,1fr); gap:12px; }
  .hero-fsg h1 { font-size:clamp(50px,7.5vw,76px); }
  .hero-facts { margin-top:-32px; margin-bottom:48px; gap:16px; }
  .hero-facts > div { padding:24px 20px; }
  .hero-facts > div:first-child, .hero-facts > div:last-child { padding-inline:20px; }
  .hero-facts strong { font-size:23px; }
  .publication { padding:26px; }
}
@media(max-width:640px) {
  .hero-fsg { padding-block:56px 74px; }
  .hero-inner { display:block; }
  .hero-copy { max-width:none; }
  .hero-art { position:absolute; width:320px; right:-155px; top:5px; opacity:.18; pointer-events:none; }
  .hero-fsg h1 { max-width:460px; font-size:clamp(44px,11vw,68px); }
  .hero-fsg .eyebrow { max-width:none; margin-inline:0; justify-content:flex-start; letter-spacing:.08em; font-size:10px; }
  .hero-lede { max-width:480px; font-size:16px; }
  .hero-facts { grid-template-columns:1fr; gap:12px; margin-top:-28px; margin-bottom:36px; }
  .hero-facts > div, .hero-facts > div:first-child, .hero-facts > div:last-child { display:flex; align-items:center; gap:18px; padding:22px; }
  .hero-facts strong { flex:0 0 42%; margin:0; font-size:20px; }
  .hero-facts > div > span { font-size:12px; }
  .founders { padding:28px 18px; }
  .findings-grid article { padding:24px; }
  .publication { padding:24px 20px; }
  .filter-tabs { flex-wrap:wrap; }
  .filter-tabs button { padding-inline:10px; font-size:13px; }
  .hero-actions { align-items:flex-start; }
}
@media(prefers-reduced-motion:reduce) { .button { transition:none; } }